Polycystic ovary syndrome (PCOS) is the most common cause of female infertility, keeping thousands of women from having children of their own. Until recently, doctors have been split about how to treat PCOS. One group favors Clomid (known as clomiphene in the United States and Clomifene internationally), while the other group favors Metformin (which also goes by the names Glucophage, Diabex, Diaformin, Fortamet, Riomet, and Glumetza).
A recent study published in The New England Journal of Medicine answers that question. In it, researchers compared Clomid to Metformin as treatments for PCOS, and found that Clomid was the more effective infertility treatment. The study followed a total of 626 infertile women with PCOS, and found that the pregnancy rate was three times higher with clomiphene.
Side effects of Clomid
Although clomid was found to be more effective than Metformin at helping women get pregnant, the drug does have some side effects. According to one researcher, “Multiple birth, at a rate of 6 percent as found in the study, is a complication. Queasiness, nausea and diarrhea were some of the more common effects.
“It’s not life threatening, [but] twins usually deliver a month early, on average. So the risks of prematurity are higher…”.
Using Clomid to treat female infertility is hardly new, and the effectiveness of Clomid is hardly news. The lead researcher on the study said he “thinks the study will help doctors more effectively manage the “fertility problem, adding, “It’s not a new treatment; it’s figuring out what the best treatment is out there.